Search results for "PsyArXiv|Psychiatry"

TALPID3/KIAA0586 Regulates Multiple Aspects of Neuromuscular Patterning During Gastrointestinal Development in Animal Models and Human

2021

TALPID3/KIAA0586 is an evolutionary conserved protein, which plays an essential role in protein trafficking. Its role during gastrointestinal (GI) and enteric nervous system (ENS) development has not been studied previously. Here, we analyzed chicken, mouse and human embryonic GI tissues with TALPID3 mutations. The GI tract of TALPID3 chicken embryos was shortened and malformed. Histologically, the gut smooth muscle was mispatterned and enteric neural crest cells were scattered throughout the gut wall. Analysis of the Hedgehog pathway and gut extracellular matrix provided causative reasons for these defects. Interestingly, chicken intra-species grafting experiments and a conditional knockou…

Cognition, metacognition and the patient perspective : new ways to evaluate and rehabilitate schizophrenia patients in forensic psychiatric care

2016

This research focused on factors associated with schizophrenia as well as on the feasibility and effectiveness of group metacognitive training (MCT) in schizophrenia patients with a history of violence in a high-security forensic hospital setting. One of the aims was to scrutinize reasoning ability in regards to jumping to conclusions (JTC) cognitive bias and the expression of cognitive insight (insight into one’s own thinking), a metacognitive ability. A second aim was to examine the associations of these factors with each other and with insight into illness and delusions. Moreover, the patients’ health-related quality of life (HRQOL) was explored. A further objective was to study the pote…

Antennal lobe representations are optimized when olfactory stimuli are periodically structured to simulate natural wing beat effects

2014

Animals use behaviors to actively sample the environment across a broad spectrum of sensory domains. These behaviors discretize the sensory experience into unique spatiotemporal moments, minimize sensory adaptation, and enhance perception. In olfaction, behaviors such as sniffing, antennal flicking, and wing beating all act to periodically expose olfactory epithelium. In mammals, it is thought that sniffing enhances neural representations; however, the effects of insect wing beating on representations remain unknown. To determine how well the antennal lobe produces odor-dependent representations when wing beating effects are simulated, we used extracellular methods to record neural units an…

Using the Storytelling Method to Hear Children’s Perspectives and Promote Their Social-Emotional Competence

2019

This study investigated the use of a playful, narrative, vignette-based method, called Story Magician’s Play Time (SMPT), in supporting children’s social-emotional reasoning and in helping children practice their social skills. We set out to examine (a) in what ways children use SMPT sessions to explore social interaction situations and to practice social skills, and (b) what story content and narrative play behavior during the SMPT sessions reveal about the social-emotional competence of children, in terms of acquisition and performance skills. The data were collected during SMPT storytelling sessions where 5- to 6-year-old children narrated stories of familiar but challenging daily situa…

“Det sitter i veggene”. Materialitet og mennesker i distriktspsykiatriske sentra

2009

This dissertation examines the impact that the materiality of institutions has on patients and staff. Fieldwork has been carried out at five district psychiatric centres (Distriktspsykiatriske sentra, DPS) that were originally built as tuberculosis institutions. The patients’ and employees’ experiences of being present in the physical and social space of these institutions has been examined, interpreted and reflected upon. The paper provides knowledge about the significance institutions’ materiality and inner life has on the informants, and how the informants influence the materiality. Background Mental health care has moved away from institutions and towards the local community. The treatm…

Mental health profiles of Finnish adolescents before and after the peak of the COVID-19 pandemic

2023

Abstract Background The COVID-19 pandemic has had implications for adolescents’ interpersonal relationships, communication patterns, education, recreational activities and well-being. An understanding of the impact of the pandemic on their mental health is crucial in measures to promote the post-pandemic recovery. Using a person-centered approach, the current study aimed to identify mental health profiles in two cross-sectional samples of Finnish adolescents before and after the peak of the pandemic, and to examine how socio-demographic and psychosocial factors, academic expectations, health literacy, and self-rated health are associated with the emerging profiles. Methods and findings Surv…

Stress in emergency telephone number operators during the COVID-19 pandemic: the role of self-efficacy and Big Five personality traits

2022

BackgroundEmergency telephone number operators experience many challenges in their work during the COVID-19 pandemic. Their personality traits and self-efficacy may act as important factors in their level of perceived stress. The aim of this study was to determine the relationship between Big Five personality traits, self-efficacy and perceived stress among emergency tele-phone number operators during the COVID-19 pandemic.Participants and procedureOne hundred emergency telephone number operators participated in the study. The Perceived Stress Scale (PSS-10), Ten Item Personality Inventory (TIPI) and Generalized Self Efficacy Scale (GSES) were used.ResultsEmergency telephone number operator…

Editorial: Neurobehavioural Mechanisms of Resilience and Vulnerability in Addictive Disorders

2021

Trajectory Analysis of Suicidal Ideation in Spanish College Students Using Ecological Momentary Assessment.

2022

IntroductionSuicide is a preventable death in young people. It is well known that suicide behavior is a multicausal phenomenon. However, suicidal ideation (SI) commonly underlies suicide, and Ecological Momentary Assessment (EMA) can help us to better characterize it and its risk and protective factors in the short term. We aimed, first, to investigate the estimated prevalence and trajectories of SI in a community sample of Spanish college students using an EMA methodology and, second, explore the associations between risk and protective factors and SI categorized as moderate or low.Materials and MethodsA total of 737 participants followed the EMA during a period of 6 months. We estimated t…

I Cannot Read Your Eye Expression: Suicide Attempters Have Difficulties in Interpreting Complex Social Emotions

2020

International audience; Background: The ability to differentiate emotions in social contexts is important for dealing with challenging social situations. Suicide attempters show some difficulties in emotion recognition that may result in hypersensitivity to social stress. However, other studies on the recognition of social complex emotions found that suicide attempters have similar performances as depressed non-attempters. Objectives: To investigate differences in social emotion recognition in patients with current Major Depressive Episode (MDE) with and without history of suicide attempt. Methods: Two hundred and ten patients with MDE were recruited among whom 115 had lifetime history of s…